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Dethiobiotin synthetase

WebJan 1, 1979 · This chapter presents an overview of dethiobiotin (DTB) synthetase. The interrelationship between 7,8-diaminopelargonic acid and DTB has been first established … WebIn addition, the synthetase domain is homologous to dethiobiotin synthase, 198 an enzyme that forms an iminophosphate intermediate during catalytic turnover. 199 The …

RCSB PDB - 1A82: DETHIOBIOTIN SYNTHETASE FROM …

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Dethiobiotin Synthetase: The Carbonylation of 7,8 …

WebThis article is cited by 32 publications. Andrew P. Thompson, Wanisa Salaemae, Jordan L. Pederick, Andrew D. Abell, Grant W. Booker, John B. Bruning, Kate L. Wegener, Steven W. Polyak. Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes. Webdethiobiotin synthetase Synonyms: Evidence for Translation: Charge (pH 7)-7.44 Kyte-Doolittle Hydrophobicity Value: 0.323 Molecular Weight (kDa) 23.6 Isoelectric Point (pI) 5.02 Subcellular localization. Individual Mappings: Localization Confidence PMID; Cytoplasmic ... WebJan 1, 1979 · This chapter presents an overview of dethiobiotin (DTB) synthetase. The interrelationship between 7,8-diaminopelargonic acid and DTB has been first established when both vitamers have been found to satisfy the biotin requirement of … tsubaki conditioner refill

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Category:[61] Dethiobiotin synthetase - ScienceDirect

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Dethiobiotin synthetase

RCSB PDB - 1DTS: CRYSTAL STRUCTURE OF AN ATP DEPENDENT …

WebThe levels of dethiobiotin synthetase in Escherichia co2i have been increased 6-fold over the wild type when pre- pared from a X-lysogen carrying the bioD gene under phage control. The purification procedure employed gave a nearly … WebMar 31, 1998 · The ATP-dependent enzyme dethiobiotin synthetase from Escherichia coli catalyses the formation of dethiobiotin from CO2 and 7, 8-diaminopelargonic acid. The …

Dethiobiotin synthetase

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WebMay 8, 1995 · 1DAD, 1DAE, 1DAF, 1DAG, 1DAH, 1DAI. PubMed Abstract: The crystal structures of six complexes of homodimeric Escherichia coli dethiobiotin synthetase with a variety of substrates, substrate analogs, … WebMay 8, 1995 · These include (1) the binary complex of dethiobiotin synthetase and the N7-carbamate of 7,8-diaminononanoic acid, (2) the binary complex of enzyme and the alternate substrate, 3-(1-aminoethyl)-nonanedioic acid, (3) the binary complex of enzyme with the product ADP, (4) the quaternary complex of enzyme, ADP, the N7-carbamate of 7,8 ...

WebPubMed WebMar 31, 1998 · The ATP-dependent enzyme dethiobiotin synthetase from Escherichia coli catalyses the formation of dethiobiotin from CO2 and 7, 8-diaminopelargonic acid. The reaction is initiated by the formation of a carbamate and proceeds through a phosphorylated intermediate, a mixed carbamic phosphoric anhydride ... Macromolecules

WebSep 5, 1995 · Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF 3 -diaminopelargonic acid and enzyme-MgADP-dethiobiotin … WebDethiobiotin synthetase, DTBS, (PDB id = 1a82) plays an important role in the biotin synthetic pathway. Better known as vitamin H, all organisms require biotin. Biotin’s necessity for life lies in its identity as a prosthetic group for the enzymes that catalyze the many biological carboxylation and transcarboxylation reactions (1).

WebGSE12663: virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages: GSE42863: Flagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii

WebApr 7, 2024 · Atlanta, city, capital (1868) of Georgia, U.S., and seat (1853) of Fulton county (but also partly in DeKalb county). It lies in the foothills of the Blue Ridge Mountains in … tsubaki connecting linkWebNov 1, 2000 · Sequence analysis of this fragment revealed that it is closely related to a family of ATP-dependent enzymes that also includes dethiobiotin synthetase and the synthetase domains of two amidotransferases involved in cobalamin biosynthesis, cobyrinic acid a,c-diamide synthase (CobB) and cobyric acid synthase (CobQ). tsubaki couplingWebApr 30, 2012 · The Two-Step Synthesis of DTB from KAPA. (A) In bacteria, DTB is synthesized from KAPA by two distinct enzymes encoded by bioA and bioD genes, respectively, catalyzing successively DAPA-AT and DTBS reactions. AdoMTOB, S -adenosyl-2-oxo-4-methylthiobutyric acid. tsubaki conditionerWebSep 5, 1995 · Mechanism of an ATP-Dependent Carboxylase, Dethiobiotin Synthetase, Based on Crystallographic Studies of Complexes with Substrates and a Reaction Intermediate. Biochemistry 1995, 34 (35) , 10985-10995. tsubaki drive chainWebSpecifically, DTBS allows for the ATP-dependent formation of dethiobiotin from 7,8-diaminopelargonic acid (DAPA) and CO 2 by catalyzing a ureido ring formation(4). The … tsubaki cool shampooWebThe creative, dynamic city is so popular, in fact, National Geographic selected Atlanta as one of the top destinations to visit in the National Geographic Best of the World 2024 list, … tsubaki double speed chainWebMay 8, 1995 · The crystal structures of six complexes of homodimeric Escherichia coli dethiobiotin synthetase with a variety of substrates, substrate analogs, and products … tsubaki clutch